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Betaine prevents heart attack and damage after injection of toxic drug, isoprenaline PDF Print E-mail
Written by Greg Kunin   
Wednesday, 20 January 2016 10:14

Betaine prevents heart attack and damage after injection of toxic drug, isoprenaline.
African Journal of Biochemistry Research, Vol.1 (6), pp. 117-123, November 2007
Protective effect of betaine on changes in the levels of protein, glycoproteins and amino acids in isoprenaline-induced myocardial infarction in rats
B. Ganesan, R. Rajesh, R. Anandan, and N. Dhandapani

Abstract edited by Dr. Kunin for clarity:

In this research rats were injected with isoprenaline (similar to adrenalin), so as to cause myocardial infarction, identical to heart attacks in humans. The experiment included a second group of rats that were pre-treated with betaine. The outcome showed a dramatic protective effect of betaine, evidenced by survival and significant changes in the levels of protein, glyco-protein and amino acids in the betaine treated animals after the injection of isoprenaline.

diagram of the human heart showing its various parts labeled for clarity

Pre-treatment with betaine (by mouth) significantly prevented the isoprenaline-induced rise in the levels of troponin-T and creatine phosphokinase (CPK), signs of heart muscle damage. It also lowered amino acid signs, specifically, taurine, aspartate, glutamate, arginine, hydroxy-proline and homocysteine, which appear in the blood after heart attacks. Reduced damage was also evidenced by reduced glycoprotein components (e.g. hexose and hexosamine) and there was also a decrease in lipid peroxidation. In fact, the heart damage was so limited that tissue peroxides remained at normal levels, comparable to the uninjected control animals.

These results indicate that Betaine was able to stabilize heart cell membranes (in the face of isoaprenaline, which is known to cause heart attacks. Betaine protection is probably by its antioxidant property against free radicals.

Dr. Kunin’s Comment:

We also know that Betaine supports production of methionine and SAM and this is independent of folate and cobalamin (B12). Thus, my interpretation is that betaine can convert TOXIC homocysteine into ESSENTIAL methionine. That is the key, for Methionine makes SAM, which is needed to make hundreds of methyl products required to keep us healthy. By delivering its methyl carbon, SAM becomes SAH, which can mesh with the Cystathionine enzyme, CBS, and thus liberate cysteine, required for synthesis of glutathione and taurine. These final products are protective for heart cells and against free radicals generated by the heart muscle itself. Consider this: the heart muscle MUST generate energy for a lifetime and free radicals are a continuous by-product of this continuous activity. Betaine is an important protective factor in this amazing feat. It is a major anti-aging nutrient, and not only in the heart, but also the liver and kidneys.

Note: There are many research publications regarding isoprenaline and myocardial infarcts. Curcumin and many other herbs have been tested and were successful, so was DMSO. Not only are free radicals considered important but ischemia, low blood flow, due to partial coagulation of blood is also recognized. But the most natural and least toxic approach most likely is Betaine.

Incidentally, beta-adrenergic drugs are known to oxidize into toxic products, such as adrenochrome. Abram Hoffer, father of megavitamin therapy, researched the use of vitamin C as an antidote to adrenochrome in the treatment of schizophrenia. Free radical biochemistry is a factor in many acute and chronic illnesses, especially those that involve inflammation.

In that regard, following the lead of Dr. Hoffer, we have included 1000mg per packet of Vitamin C (ascorbic acid) in Ola Loa ENERGY and SPORT and 500 mg in Ola Loa REPAIR. Inflammatory challenges, such as viruses, bacteria, chemicals and physical-psychological stress affects everyone.

Ola Loa is the first Methylation Multivitamin with over 20 years leading the way in Methylation Support Nutrient Supplements.

Description: Betaine, TMG, protective against heart attack.

meta tags: Betaine, TMG, heart attack, heart protection, methylation, free radicals, antioxidant, isoprenaline

Last Updated on Wednesday, 20 January 2016 11:12
HO HO HO and Keep The Heart Attacks Away! PDF Print E-mail
Written by Greg Kunin   
Tuesday, 24 December 2013 16:44

Healthy hearts for the holidaysThe holidays are in full swing and with it comes an increase in heart attacks. How could it be during this incredible month of celebration and joy that there could be an increased risk of death to go along with it?

As far as I am concerned it's very simple. Starting with Thanksgiving and continuing through to New Years, we let our hair down and let loose with an incredible amount of good cheer which includes a big increase in the consumption of animal protein which leads to increased homocysteine levels which leads to an increase in heart attack. It's sobering to remember that Chambers & McGregor showed that the average healthy male had a decrease of 85% in blood flow by simply consuming the amount of methionine found in two steaks.

This situation gets worse with the increase in alcohol and sweets during the festive holidays. Older people with elevated homocysteine are at even greater risk. It's not just the effects of tryptophan from the turkey you are feeling, it's the decrease in blood flow and the damage to your cells.

So enjoy the holidays, slow down on the consumption side and remember Ola Loa provides the B6, B12, Folate and most importantly the TMG-Betaine which support healthy homocysteine levels. Ola Loa is also a great way to end a meal and many use it as an alternative to desert. Feel good...Drink Ola Loa

Last Updated on Thursday, 26 December 2013 11:41
Cyanide Poisoning Confirms Need For Hydroxy-B12 PDF Print E-mail
Written by Gregory Kunin   
Tuesday, 11 June 2013 00:00

"Brazil's health ministry urgently requested 140 of the cyanide-treatment kits containing the medicine hydroxocobalamin"*


In February, a terrible nightclub fire took the lives of 236 people in Brazil leaving over 140 people with acute Cyanide poisoning due to the combustible materials that outgassed Cyanide. Currently the standard treatment for acute cyanide poisoning is a very special form of Vitamin B12 that is used in Ola Loa Products, HydroxyCobalamin. I find it amusing that this vitamin is being referred to as a "medicine." Ironically, virtually all vitamin B12 supplements contain the cyanide form of B12 known as CyanoCobalamin. This form of Cobalamin is already bound to a cyanide molecule and can't detoxify cyanide.
Image of the Brazilian nightclub ruins in which 238 people lost their lives.

Sadly there was an insufficient supply of the correct form of Vitamin B12 in Brazil and at the request of the Brazilian Government the United States sent over 140 kits of this very hard to get form of Vitamin B12.

What comes as a surprise for many is that not only are there several forms of Vitamin B12, but that some forms are much better than others. Ola Loa has been at the forefront of making people aware of the significant benefits one gets from HydroxyCobalamin which is in fact the natural transport factor of vitamin B12 offering great absorption and usage.

What Brazil shows us is you shouldn't wait for acute Cyanide poisoning to get the right form of Vitamin B12. Remember that HydroxyCobalamin is the only form of Vitamin B12 that detoxifies Cyanide and for vegans, vegetarians and smokers who often times run low B12 and high cyanide this can be a significant health risk.


Gregory M. Kunin
Wishing you good health and Ola Loa!


Last Updated on Sunday, 16 June 2013 10:29
Mass Shooting Events: A Medical Problem vs. Gun Control PDF Print E-mail
Written by Gregory Kunin   
Monday, 14 January 2013 21:44

image graphic - NO PROZAC!With the recent shootings in New Town, CT there has been a justifiable outcry for something to be done but I'm worried that our representatives in Washington and elsewhere will overreach and not make us any safer. Our elected officials seem obsessed with the idea of gun control and are doing a disservice by referring to certain weapons as "assault weapons". The fact is all firearms in the wrong hands are potentially "assault weapons" and with over 300 million firearms in circulation gun control does very little from keeping guns out of the hands of deranged individuals determined to get their hands on a firearm. What New Town shows us, like other tragedies of this type is that we don't have a gun control problem as much as a medical problem. What's going on with these people to commit such horrible acts? And is there a way to work with these people before they become killers? I believe there is and the Orthomolecular approach is the answer.

It's interesting to note that in many of the cases of mass shootings over the last 20 years the perpetrators were either on antidepressants, coming off antidepressants or changing to another drug. And since the epidemic use of these medications the frequency of these type of events has increased.

The FDA is so concerned about these medications they have warnings about them on their website:

"Clinical Worsening and Suicide Risk: Patients, their families, and their caregivers should be encouraged to be alert to the emergence of anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness), hypomania, mania, other unusual changes in behavior, worsening of depression, and suicidal ideation, especially early during antidepressant treatment"

Most troubling is that many of these people were being treated by health professionals who did not have the advantage of the Orthomolecular approach, of understanding Nutrition, Pollution, Stress (hormone function), Genetics and Blood Flow. This is where I believe, the system has failed us. I am most frustrated about this in so much as the Orthomolecular approach was developed by a group of psychiatrists in the 1960's who found that damaged people could be saved by simply understanding their natural chemistry and correcting the deficiency. In a nutshell those who were nutrient deprived were not at their best, physically or mentally. Put another way, Nutrient Deficiency can lead to PSYCHOSIS! One only has to see a woman who has recently given birth, that is both vitamin B12 and Folate deficient who loses control and injures her own baby to understand this. Extreme postpartum depression is in fact a nutrient deficiency disease as is Pellagra. But ask yourself when was the last time a pregnant woman or an individual being put on antidepressants was checked for their blood vitamin levels?

Sadly modern medicine doesn't get it. The Orthomolecular approach goes a step further and asks, "Are you Toxic?" It's a well known fact that heavy metals, such as lead, mercury, and aluminum can damage the brain. Interestingly enough most of the popular antidepressants today contain large quantities of Fluoride a known neurotoxin that damages the brain. Prozac is approximately 18% Fluoride.

In a 2011 study from China, researchers found an increase in brain cell death (apoptosis) from exposure to fluoride (VIEW STUDY). Also from China a 2009 report shows that Fluoride and lead can decrease learning ability (VIEW STUDY). Both studies show very simply that Fluoride damages the brain. Now ask yourself were these individuals drinking tap water containing fluoride, were they seeing a dentist regularly that was giving them fluoride rinses, did they use mouthwash which contains high levels of Fluoride, and were they eating and drinking foods rich in fluoride. Also ask yourself is it possible that these people were contaminated with other toxins including heavy metals like lead, mercury, aluminum, etc. all of which are known to have a deleterious effect on brain function.  

For years many in the autism community have been concerned, rightfully so, with the amount of heavy metals, mercury, in particular, that is found in vaccines, including the FLU shot, which I would never recommend for anyone to take. Let's not forget that as we have increased the number of vaccines in use today so too has there been an increase in these awful violent events.

Lastly, consider blood flow and circulation. In 1999 our Director of Research, Dr. Richard Kunin, presented his findings on coagulation and low blood flow in his autistic children to the DAN! Conference (Defeat Autism Now). It was alarming that 7 of his 12 autistic cases showed elevated homocysteine which can reduce blood flow (Ischemia) which in fact is the most dangerous NeuroToxin. This is very important to understand. We're not talking no blood flow, simply low blood flow. Ask yourself, how many people are currently taking antidepressants when in fact they have a low blood flow disorder caused by elevated homocysteine or other clotting factors (lipoprotein (a), factors 2 and 5 and Small Dense LDL)

Obviously most of the people that take antidepressants or get vaccinated are not going to become raving homicidal maniacs, but one has to ask how much damage is occurring for the common man from these treatments? The "dumbing" down effect. Clearly some people are at greater risk than others, especially with their ability to detoxify and the Orthomolecular approach, I believe, gives us the greatest insight in working with these at risk individuals. I think it is clear that before resorting to toxic therapy it is essential to identify weakness and vulnerability in these individuals to potentially avoid tragedies as we have seen. Our individual chemistry is the place to start and as much as some people want to control all guns ultimately it comes down to the individual not the firearm that commits the act. It may sound cliche but guns don't kill, people do.

Last Updated on Tuesday, 11 June 2013 11:00
News about VitaminB12 PDF Print E-mail
Written by Greg Kunin   
Sunday, 14 June 2009 16:00


Richard Deth, Ph.D., shows that HydroxyCobalamin (Vitamin B12) is more available in almost all tissue of the body!

Many of you have probably heard me say the form or source of an ingredient can make a huge difference. One such ingredient is Vitamin B12. Ola Loa has gone out of our way to make sure that you have access to the most available form of Vitamin B12 (HydroxyCobalamin) versus the common form of Vitamin B12 (CyanoCobalamin, just think Cyanide). At $6,000 more per kilo, is there any wonder why most other companies use the less expensive, toxic form? In the slide below, Dr. Deth shows that the body uses HydroxyCobalamin up to 300%+ better than even MethylCobalamin.

Methyl B12 chart


Drink Ola Loa and get the advantage of HydroxyCobalamin which is the natural transport factor of Vitamin B12. It's the difference you will feel.

Gregory M. Kunin
Wishing you good health and Ola Loa!


Last Updated on Tuesday, 11 June 2013 22:41
What Drives Me to Make Ola Loa? PDF Print E-mail
Written by Greg Kunin   
Saturday, 18 April 2009 16:00
I received this testimonial today and was so inspired I wanted to share it with all of you.  This is what drives me to make Ola Loa.  My mission is to make your life better and when you receive feedback like this from your customers it makes all the hard work worth it.  

"I wanted to thank you for your products. I was hesitant to try it, but I had become tired of taking pills, and have been doing it for years. I’ve always studied health and nutrition and live a very healthy lifestyle and eat very well. The past 1 ½ years I have been struggling to recover from the birth of my 3rd child (I have a 7 and 3 year old).  I was just not feeling good. Very tired, run down, exhausted, depressed, you name it, just miserable.  Then, I decided to try the Energy product. I took it and was instantly a different person (or who I was always supposed to be).  I just felt so good. My headache disappeared, I just felt awake and well.  I was curious, I thought it was the electrolytes in your product, that made me feel so good. Being under so much stress is so dehydrating, plus I live in a warm climate.  So from that day forward, I felt better. Then, I started taking the Repair product at night before bed, and after the very first night, when I woke up in the morning, I no longer had achy joints, my ankles and feet did not hurt any more.  I thought it was miraculous. I continue to feel great and take it every night after dinner.
So thank you. I was also just watching a program on TV about the benefits of DMG and I was like, ‘oh I better take that too’ but it ‘sounds familiar’.  Then I realized TMG was in your vitamins and I was already getting it! I was thrilled!
So many thanks from a new loyal customer."

Anne L.

When you read something like this and realize that someone took the time to go out of their way to write it and send it to us it's even more impressive.  All I can say is thank you, This made my day :)

Wishing you good health and Ola Loa!


Gregory M. Kunin

Founder & CEO, Ola Loa Products/

Last Updated on Wednesday, 22 April 2009 09:38
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